• Researchers find protein that plays a role in neuropathic pain
  
  Drs. Yves De Koninck, from Université Laval, and Michael Salter, from the Hospital for Sick Children, have discovered that a protein called Brain-Derived Neurotropic Factor (BDNF) helps mediate neuropathic pain. Neuropathic pain, a chronic pain of nerves, causes a change called microglia in spinal cord cells. Drs. De Koninck and Salter, both CIHR-funded researchers, have discovered that BDNF helps microglia communicate pain to nerve cells in the spinal cord. By disrupting this communication network, the researchers relieved neuropathic pain in mice. This discovery will likely lead to the development of new therapies for neuropathic pain sufferers.
  
  
• Discovery of protein provides insights into nerve cell death
  
  Dr. David Kaplan, a CIHR-funded researcher from the Hospital for Sick Children, has discovered a protein called p63 which helps with nerve cell death during pre- and post-birth development. At birth, the human body has twice the number of nerve cells required. The body disposes of the excess cells with the help of p63. If this process breaks down however, the nervous system can't function properly. Dr. Kaplan suspects that p63 may also determine whether nerves cells die in neurological diseases, such as Alzheimer's and Parkinson's. Future research will look into how to regulate this protein, and then develop novel treatments for those who suffer from irregular nerve cell death.

December 12, 2005

• Bergeron receives Prix du Québec - Wilder-Penfield
  
  On November 8, Dr. Michel G. Bergeron, Director of the Infectious Disease Research Center (IDRC) at Université Laval, received the 2005 Wilder-Penfield prize. Each year the prize, which is given by the province of Quebec, recognizes the outstanding contribution of a researcher to biomedical sciences. Dr. Bergeron received the award for his lifetime contributions towards microbiology and immunology. 

December 6, 2005

• Wrana receives Paul Marks Prize for Cancer Research
  
  Dr. Jeff Wrana, a CIHR-funded researcher, is one of three recipients of the Paul Marks Prize for Cancer Research in recognition of his achievements as a cancer research leader. Dr. Wrana, who is a Senior Investigator in Molecular Biology and Cancer at Toronto's Samuel Lunenfeld Research Institute, is being honoured for his work which is attempting to uncover whether a family of cell signaling proteins either blocks or promotes cancer growth. The award, which is presented every other year by the Memorial Sloan-Kettering Cancer Center, is named after Dr. Paul Marks whose research efforts helped develop a more potent chemotherapy and chemoprevention agents.

December 1, 2005

• World AIDS Day 2005: CIHR's efforts to defeat a deadly disease

November 30, 2005

• CIHR-funded researcher helps identify gene for debilitating vitamin B12 disease  

November 29, 2005

• Study helps reverse drug addiction in mice
  
  Dr. Yu Tian Wang, a CIHR-funded research from the University of British Columbia (UBC), has managed to reverse the drug addiction process in mice. Drug addiction stems from the loss of glutamate receptors in the brain, which supports a communications channel for pleasure and motivation. Researchers have sidestepped this problem by creating a peptide, or a small molecule made from a string of amino acids, that mimics the actions of a glutamate receptor. As a result, mice who have acquired a drug addiction are able to resume normal brain function. Dr. Wang says that this discovery may one day lead to a successful treatment for humans, but cautions that this is years away from happening.

November 21, 2005

• Babiuk receives Prix Galien
  
  Dr. Lorne Babiuk, a CIHR-funded researcher and Chair of CIHR's Institute of Infection and Immunity's advisory board, has received the 2005 Prix Galien Canada Research Award. The award recognizes outstanding research in the diagnosis, prevention or treatment of disease. Dr. Babiuk's pioneering research efforts in vaccinology and biotechnology have brought the importance of veterinary medicine and the link between animal diseases and human diseases to the forefront in Canada. Recently, his research into how viruses invade cells has enabled him to create candidate vaccines that could possibly eradicate Severe Acute Respiratory Syndrome (SARS).
  
  
• Obesity among children related to poor instruction, study shows
  
  Dr. Paul Veugelers, a CIHR-funded researcher from the University of Alberta, has determined that obesity rates among youth can climb due to poor eating habits with their families. Of the 4,000 Nova Scotia children surveyed, research suggests that waistlines can expand if they don't bring brown-bag lunches, neglect to eat breakfast or eat supper in front of the television. Dr. Veugelers says that if children are taught to eat regular meals and consume home-cooked foods with their families, they will not become overweight. Calgary Herald, September 13, 2005, p.B13.
  
  
• Genetic discovery regarding vision problems in the retina
  
  Dr. Torben Bech-Hansen, a CIHR-funded researcher from the University of Calgary, has made a genetic discovery with regards to vision problems in the retina. In a mutated retina, structural damage between photoreceptors and other neurons is the result of an obstruction in communications channels. Dr. Bech-Hansen asserts that this damage could be the result of an abnormal calcium protein channel. The findings should lead to new treatments for vision problems, such as near-sightedness and night blindness.

November 16, 2005

• CIHR Releases Research Results to Inform the Development of Benchmarks for Wait Times

November 15, 2005

• Investment in health research will help reduce Canada's productivity gap

  In an editorial, the Globe and Mail declares that one of the ways Finance Minister Ralph Goodale can reduce Canada's productivity gap is by increasing investments in health research. According to the newspaper, if Minister Goodale 'channels more funding' into CIHR, the agency's funded researchers will hatch the next wave of biotech companies and help commercialize university research. The paper acknowledges Dr. Bernstein's assertion that these funded projects are the 'wisest, efficient and most prudent investments any society can make.' They will lead to ever-more-valuable products with better equipment and a more highly-skilled workforce. Globe and Mail, November 8, 2005, p.A18.

November 10, 2005

• Dr. Singh's column in Healthcare Quarterly highlights potential of vaccines against Lassa fever, Marburg and Ebola viruses
  
  In the latest edition of Healthcare Quarterly, Dr. Bhagirath Singh, Scientific Director for CIHR's Institute of Infection and Immunity, highlights the research efforts of Drs. Heinz Feldmann and Steven Jones. Earlier this year, Drs. Feldmann and Jones, two CIHR-funded researchers, announced the development of vaccines that have the potential to eradicate the Lassa fever, Marburg and Ebola viruses in humans.

November 9, 2005

• MP Newsletter: Your Health Research Dollars at Work - Fall 2005

November 7, 2005

• Keynote Address to the Canadian Academies of Health Sciences: "The Promise of the Health Sciences in the 21st Century," by Dr. Alan Bernstein

November 4, 2005

• Dr. Remi Quirion, SD for CIHR's INMHA, suggests that psychiatry should be a clinical neuroscience discipline in a commentary for JAMA

October 28, 2005

• Presentation to the Standing Committee on Finance Pre-Budget Hearings by Dr. Alan Bernstein

October 27, 2005

• Health Research News Alerts

October 26, 2005

• Genetic cause of speech defect discovered
  
• New antifreeze protein may allow longer storage of transplant organs

October 24, 2005

• International team uncovers molecules that will help in hepatitis treatment
  
  Dr. Paul Kubes, a CIHR-funded immunologist from the University of Calgary, has led an international team in the discovery of a molecule called Vascular Adhesion Protein-1 (VAP-1) which battles hepatitis. The liver filters contaminated blood leaving the stomach and intestines using tiny blood vessels called sinusoids. Sometimes, white cells stick to these sinusoids and then Hepatitis A develops. VAP-1 acts as a lubricant and prevents these white cells from sticking in the first place. The discovery offers new hope for the development of less invasive treatments for hepatitis patients.
  
  
• Molecule suppresses NK cell activity, according to study
  
  Dr. André Veillette, a CIHR-funded researcher from Institut de recherches cliniques de Montréal (ICRM), has discovered a molecule, EAT-2, that suppresses the killer function of natural killer (NK) cells. NK cells recognize and kill cancer cells as well as cells infected by viruses that cause hepatitis and herpes. Dr. Veillette has established that suppressing EAT-2 results in the production of NK cells, which could be used in combination with chemotherapy and radiotherapy to improve anti-cancer treatments.
  
  

• Scientist uncovers gene related to speed of tuberculosis development
  
  Dr. Edwin Shurr, a CIHR-funded researcher from McGill University Health Centre, has discovered a gene called NRAMP1 that controls the speed at which people develop tuberculosis. The gene's discovery will provide scientists with further insights into the disease's mechanism. Le Quotidien, August 17, 2005, p. 25 and Red Deer Advocate, August 18, 2005, p.A6.

• Study examines work absenteeism rates among female breast cancer sufferers
  
  Dr. Elizabeth Maunsell, a CIHR-funded researcher from Laval University, examined work absenteeism among female breast cancer sufferers. With the help of her research team, she discovered that breast cancer survivors were not away from work for longer periods than other working women.  

• Study suggests genetics affect the severity of metabolic syndrome in obese people

October 17, 2005

• Artificial intelligence program unlocks gene secrets
  
  In the August 28 edition of Nature Genetics, CIHR-funded researcher Dr. Brendan Frey outlines how a computer analysis changed contemporary views of how genes work. Using samples from 37 mouse tissues, Dr. Frey's artificial intelligence computer program revealed thousands of genetic instructions - including a startling one that showed there are no new protein-coding genes to be discovered (which are largely responsible for managing cells and determining everything form eye colour to disease). By better understanding genes, Dr. Frey hopes to gain further insight into gene malfunction and disease.

October 14, 2005

• Diane Finegood to receive George Bray Founder's Award

October 11, 2005

• Targeting future obesity research -- Canadian experts identify critical knowledge gaps

September 29, 2005

• $582,234 in technology transfer support awarded to a joint network involving U of C, MRC, RDC and SAIT

September 28, 2005

• Health Research News Alerts

September 22, 2005

• Government of Canada offers $500,000 in financial support to train specialists in technology enhancement (French only)

September 20, 2005

• Government of Canada announces $17.1 million to fund knowledge and technology
  
  
• $1.54 million in technology transfer support announced at UNBF
  
  
• $2.1 million in technology transfer support for southwestern Ontario universities

September 19, 2005

• CIHR partners to support the 96th annual Canadian Public Health Association Conference 
  
  CIHR is proud to partner with the Canadian Public Health Association (CPHA), the Canadian Institute for Health Information - Canadian Population Health Initiative (CIHI-CPHI), and the Public Health Agency of Canada (PHAC), and in association with the Statistics Canada's Health Statistics Data User's Conference 2005 hosts the 96th annual CPHA conference from September 18 to 21, 2005. The theme of this year's conference is "Mapping the Future of Public Health: People, Places and Policies", focusing on how the places in which Canadians live, work, play and learn affect their health, and how related public policies can foster longer, healthier and more productive lives.

September 16, 2005

• Trial results show women with dense breasts, under the age of 50, who are pre-menopausal may benefit from digital mammography

September 15, 2005

• New Research Chair at University of Ottawa to advance understanding of neurological and psychiatric disorders
  

September 14, 2005

• Two genes may play a role in cancer development
  
  Dr. Wei Xiao, a CIHR-funded researcher from the University of Saskatchewan, has discovered a pair of closely-related genes that may govern the development of cancer. One gene, dubbed Beauty, programs an enzyme called Mms2 to repair damaged DNA so that the cells can reproduce healthy copies of themselves. The other gene, dubbed Beast, codes an enzyme called Uev1A to divide cells in an effort to fight bacteria or viruses. Beast's ability to promote cell division makes it an ideal candidate to become a gene that causes cancer. If Dr. Xiao can prove his theory, this could lead to further tests that will allow earlier treatment and prevention of cancer.
  
  
• Message from the President about IHSPR Transition
  

September 13, 2005

• Message to Dr. Bruce McManus by Dr. Alan Bernstein, CIHR President

September 1, 2005

• Biochemical switch provides insight into learning
  
  Dr. Joachim Herz, a CIHR-funded researcher from UT Southwestern Medical Center, has discovered a biomedical switch in mice that plays an important role in learning capacity. In the brain's hippoccampus, which stimulates learning and navigation, a protein called reelin binds with a receptor called Apoer2. Apoer2, in turn, amplifies activity of another receptor called NMDA and allows for increased learning capacity. At birth, an extra string of amino acids (building blocks of proteins) facilitates the connection between Apoer2 and NMDA. Dr. Herz has found that if this biochemical switch is removed or cut somehow, the mice slow down in their ability to learn. By understanding reelin, and its connection to receptors such as Apoer2, Dr. Herz will gain further insight into neurodegenerative diseases that may cause the switch to be cut in the first place - such as Alzheimer's.

August 25, 2005

• UBC makes ninth place in The Scientist's pipeline power
  
  A recent study, conducted by an intellectual property consulting firm for The Scientist magazine, determined that the University of British Columbia (UBC) placed ninth in the 'pipeline power' scale. This pipeline is based on multiplying the number of life science patents, achieved by a particular university, by four measures of quality (growth, impact, general applicability, and originality). CIHR funds UBC health researchers and supports commercialization initiatives, and applauds the school's international achievement in the field of life sciences. Based on this ranking, UBC placed ahead of other American schools, such as Columbia University and John Hopkins University. Vancouver Sun, August 25, 2005, p. A10.

August 24, 2005

• INMHA announces New International collaboration
  
  
• Bacterium senses when immune system is weak and attacks bloodstream
  
  In the July 29 issue of Science, CIHR-funded Dr. John Alverdy from the University of Chicago describes how a bacterium called pseudomonas aeruginosa infects the human bloodstream. The bacterium, which resides in people's bowels, senses when the human immune system is weak and uses its own genes to break through the bowel wall into the bloodstream to invade tissue. Resulting illnesses include gut-derived sepsis, or widespread pseudomonas infection - which can kill a patient inside of days. Dr. Alverdy would like to develop novel ways to intervene and stop this lethal process from happening at all.
  
  
• Bernstein talks about implications of NIH's ethical requirements in CMAJ
  
  In the August 16 edition of the Canadian Medical Association Journal (CMAJ), Dr. Alan Bernstein discusses the new ethical standards set by the National Institutes of Health (NIH). These stringent standards, which regard conflicts of interest, could have implications for the Canadian health research landscape. Dr. Bernstein emphasizes that disclosure, transparency and selected prohibitions will help CIHR ensure continued public confidence in Canada's health research enterprise.
  
  
• Novartis Pharma recognizes work of Canadian research team (French only)
  
  Novartis Pharma recognized the work of CIHR-funded researchers Drs. Janice Keefe and Jacques Legaré, as well as Dr. Yves Carrière. These researchers were given an award at the close of the XXV IUSSP International Population in Tours, France. The award, for best research, recognizes their collaborative demographic study called: "Developing new strategies to support caregivers of the aged in Canada: Projections of need and their policy implication."

August 15, 2005

• Discovery of brain mechanism could lead to new psychiatric drugs  
  
  Dr. Jean-Martin Beaulieu, a CIHR-funded researcher from Duke University Medical Center, has discovered a new mechanism in mice that explains how excessive levels of dopamine can exert a negative effect on the human brain. Dopamine normally sends chemical messages to brain receptors, which helps control the central nervous system; but its levels need to be regulated. Dr. Beaulieu's study determined that deficiencies with proteins called beta-arrestin 2 and Akt in the brain can cause problems with dopamine regulation. This could lead to the development of new psychiatric drugs to treat dopamine-related diseases, such as Parkinson's and schizophrenia.

August 4, 2005

• Protein discovery may lead to treatments for pulmonary illness and cancer
  
  Dr. Evangleos Michelakis, a CIHR-funded researcher from the University of Alberta, has discovered that a protein called survivin is common in cells of pulmonary hypertension sufferers as well as cancer patients. Clinical trials of drugs that successfully eliminate survivin will open the door to treatment for both diseases.  The Edmonton Journal, June 2, 2005, p.A16
  
  
• Study helps immigrant women get socially grounded  [ PDF (24 KB) | Help ]
  
  Dr. Denise Gastaldo, a CIHR-funded researcher from the University of Toronto, has uncovered some of the social problems experienced by immigrant women who have had to adjust their lives to metropolitan Toronto. The study's findings, which analyzed data collected from meetings, diary writing and photos, will help future immigrant women who experience displacement as well as limitations of social inclusion. www.nursing.utoronto.ca/immigrationguide/
  
  
• One dose of speed can cause long-term problems for potential offspring
  
  Using mice, Dr. Peter Wells, a CIHR-funded researcher from the University of Toronto, has discovered that a single dose of methamphetamine, or 'speed,' taken by the mother can cause long-term neurodevelopmental problems in their offspring - including reduced motor function. Dr. Wells now plans to see if women and children who have been exposed to the drug suffer the same toxic effects.

August 3, 2005

• Congratulations to the latest Fellow appointments to the Royal Society of Canada!
  
  
• International team reveals genomic annotation of Candida albicans
  
  Dr. André Nantel, based at the National Research Council Biotechnology Research Institute (NRC-BRI), helped lead a CIHR-funded international research team in developing a genomic annotation of Candida albicans - a single-cell fungus that resists  antibiotics and affects patients who suffer from immune system deficiencies. The annotation, or a detailed comment or explanation that provides context and significance to anything that has been mapped or sequenced (genes, DNA, etc.), will help researchers better improve upon existing treatments for those who suffer from infection.
  
  
• Study brings researchers a step closer to understanding migraines
  
  In research published recently in the Proceedings of the National Academy of Sciences (PNAS), Dr. Rhoda Blostein, a CIHR-funded researcher from McGill University, has developed an understanding of how genetic mutations produce migraines. Brain cells typically operate with the help of a 'sodium pump,' which regulates sodium and potassium levels. The genetic mutations linked to migraines can upset this pump's efficiency and lead to headaches. Understanding the process of migraine evolution will help researchers develop better treatments for those who suffer from them.

August 2, 2005

• Nurse workload affects patient care
  
  Ms. Raquel Meyer, a CIHR-funded registered nurse and doctoral candidate at the University of Toronto, has determined that a lighter workload for nurses will make hospital service better for patients - because it allows for more down time in their schedules and helps them to avoid burn-out. Ms. Meyer also determined that this will not cost the Canadian health care system any more money, as poor service leads to longer patient stays. The New Brunswick Telegraph-Journal, June 2, 2005, p. A5.
  
  
• Study may help curb postpartum depression
  
  Based on an analysis of 15 research projects involving 7,700 women dating back to the 1990s, Dr. Cindy-Lee Dennis, a CIHR-funded researcher from University of Toronto, has determined that support provided by a health professional might help prevent postpartum depression if it is geared to the individual woman based on her specific needs. Treatment could come in the form of antidepressants or psychotherapy depending on the level of depression. The Regina Leader-Post, July 7, 2005, A12.
  
  
• Regulated insulin helps keep the liver lean, study shows
  
  Dr. Sonia Najjar, a CIHR-funded researcher at the Medical University of Ohio, has determined that a liver overrun with insulin can develop resistance to this hormone and lead to greater fat production and weight gain. Regulated pulses of insulin to the liver, however, will reduce fat synthesis.

July 29, 2005

• Researchers discover cause of Bardet-Biedl Syndrome
  
  Two CIHR-funded molecular biologists at Simon Fraser University have helped isolate the cause of a potentially fatal rare disease with symptoms that are prevalent in the general population. Working with scientists at the University of California, professor Michel Leroux and post-doctoral fellow Oliver Blacque have discovered what molecular defects in primary cilia cause Bardet-Biedl Syndrome (BBS).

July 22, 2005

• Enzyme deficiency may explain stillbirths
  
  Dr. Andrée Gruslin, a CIHR-funded researcher at the University of Ottawa, has discovered that, in some women, a genetic mutation may cause an enzyme called PC4 to not activate IGF-2, a growth factor that allows a placenta to grow normally during a pregnancy. This deficiency may explain both miscarriages and delivery of stillborn children among some women - and may also lead to gene therapies. CBC News, July 19, 2005

July 20, 2005

• Research into support networks for Indigenous health workers in Canada and New Zealand receives $2 million in CIHR funding

July 18, 2005

• CIHR announces a new process for reviewing CIHR Fellowship applications
  
  
• CIHR and CFI announce a new collaboration for clinical research
  
  
• Dr. Stewart addressed Canadian Science Writers' Association Conference
  
  
• UBC researchers to examine why lung disease escalating in women
  
  
• Researchers determine that CABGs are twice as expensive in the US
  
  Dr. Louise Pilote, a CIHR-funded physician-scientist from Montreal's General Hospital, has discovered that patients who undergo coronary artery bypass graft (CABG) surgery have to pay twice as much at American hospitals than at Canadian hospitals, with little difference in clinical outcome and regardless of a shorter average length of stay. The cost difference reflects higher costs for overhead, labor and products at American hospitals which results from a non-socialized medical system. Kansas City Infozine, July 13, 2005.

July 11, 2005

• Government of Canada announces $5.4 million to fund interdisciplinary health research grants

July 8, 2005

• The Networks of Centres of Excellence (NCE) Program is launching a pilot project: the NCE New Initiative (NCE-NI)

July 7, 2005

• Dr. Bernstein's opinion piece 'Investing in African Health' was published in the Toronto Star, Tuesday, July 5, 2005, p. A13
  
  In this op-ed, Dr. Bernstein stresses the disparities that exist between developing countries and North America, Europe and Japan, and that overcoming the health challenges facing the developing world will require a collaborative effort. He highlights that the best health scientists in the world, including many from Canada, have taken the first critical steps to tackle these challenges.

June 30, 2005

• New vaccine may protect against Lassa fever virus

  A promising discovery by Drs. Heinz Feldmann and Steven Jones, CIHR-funded researchers at the National Microbiology Laboratory in Winnipeg, and American researchers, could eventually lead to the development of a human vaccine against Lassa fever. Lassa fever is a type of hemorrhagic disease common in parts of West Africa. Using a Canadian-made vaccine, the team successfully immunized four macaque monkeys against Lassa fever. Further work and testing is needed, but the finding offers hope that we will someday be able to protect people against this devastating illness.

• New research puts a fresh spin on current thinking of speech evolution in humans

June 27, 2005

• Minister Bennett and NSA Carty Attend Women in Research Committee Meeting at CIHR

June 22, 2005

• Brandon University receives its first-ever CIHR grant

June 21, 2005

• President's Message: A message to the research community on CIHR's fifth anniversary
  
  
• Pregnant women at risk for injury in summer
  
  
• Sick Kids researchers find new topical pain cream reduces pain and improves effectiveness of procedures in paediatric emergency department

June 15, 2005

• CIHR and its partners announce the June 2005 Requests for Applications and the Priority Announcements
  
  
• Dr. Branton receives RM Taylor Medal and Award
  
  Dr. Phil Branton, CIHR Scientific Director of the Institute of Cancer Research, has been named recipient of the 2005 RM Taylor Medal and Award from the Canadian Cancer Society (CCS) and the National Cancer Institute of Canada (NCIC). This annual award recognizes Dr. Branton's significant contribution to the understanding of tumour growth suppression  and regulation of cancer cell death; to the development of novel cancer therapeutics through GeminX Biotechnologies Inc. (a company that he co-founded); and to the establishment of multi-agency/institutional networks, such as the Canadian Cancer Research Alliance, which favour the best cancer research outcomes. Dr. Branton will formally receive the award, which consists of a medal and $1,000 purse, in October 2005 at a CCS board meeting.

June 9, 2005

• Vaccines may prevent death from Ebola and Marburg viruses
  
  Drs. Heinz Feldmann and Steven Jones, both CIHR-funded researchers at the Public Health Agency of Canada's National Microbiology Laboratory, have developed vaccines that can protect monkeys from lethal doses of the Ebola and Marburg viruses. The success rate of these vaccines with monkeys will likely translate into healthy findings for human beings.

June 7, 2005

• Updated Guidelines for Human Pluripotent Stem Cell Research

June 6, 2005

• "Silent" strokes linked to dementia
  
  Dr. Vladimir Hachinski, a neurology professor at the University of Western Ontario, has determined that 'silent' strokes can lead to dementia, including Alzheimer's Disease. Managing risk factors for these kinds of strokes, which include high blood pressure, elevated cholesterol, obesity, diabetes, tobacco use and sedentary lifestyle, could lead to preservation of the brain structure and function.
  
  
• Removal of spleen may help fight leukemia
  
  Dr. Yaacov Ben-David, a CIHR-funded research from Sunnybrook and Women's College Health Sciences Centre, has discovered that removal of the spleen in mice combined with antiangiogenic cancer therapy might stop the progression of leukemia. This research result may prove to be an effective treatment for humans in the fight against this deadly disease.
  
  
• Pregnancy-induced hypertension may cause cardiovascular disease late in life
  
  In a CIHR-funded study currently published in this month's edition of Obstetrics & Gynecology, Drs. Jean-Claude Forest and Yves Giguère, both researchers from Université Laval, have discovered a direct causal link between women who suffer from hypertension during their first pregnancy and the possibility of developing metabolic syndrome, which can cause cardiovascular disease.

June 2, 2005

• Researchers give hair dye green light over cancer concerns

May 27, 2005

• Study looks at causes of periodontal disease in diabetic patients [ External PDF (86 KB) | Help ]
  
  A team of researchers from Canada, the United States and Austria, including Dr. Bhagirath Singh, Scientific Director for the CIHR Institute of Infection and Immunity (III), have discovered a link between abnormal white blood cells and a higher risk for acute periodontal disease in diabetic patients. The findings will help researchers understand the likely causes of periodontitis, one of the most common complications associated with diabetes, and lead to new treatments. The study was published in the May issue of Diabetes, a journal of the American Diabetes Association.

May 26, 2005

• Structural Genomics Consortium Celebrates First Anniversary with 50 New Protein Structures Ahead of Plan.

May 20, 2005

• Re-appointment of Dr. Alan Bernstein as President of the Canadian Institutes of Health Research
  
  Dr. Alan Bernstein has been re-appointed President of the Canadian Institutes of Health Research (CIHR) by the Government of Canada following a review of his appointment by the Standing Committee on Health on May 20, 2005. For more information, please see the press release on our Website.
  
  
• ICEBERGS launches website
  
  A CIHR-funded multidisciplinary research team, called the Interdisciplinary Capacity Enhancement: Bridging Excellence in Respiratory disease and Gender Studies (or ICEBERGS), has launched a website. The team works towards developing better methods for studying chronic obstructive pulmonary disease. To find more about ICEBERGS, please visit http://www.icebergs.ubc.ca/
  
  
• Rotman appointed Chair of expert panel on commercialization
  
  On May 18, the Honourable David L. Emerson, Minister of Industry, announced the creation of a panel of experts who will advise the Government of Canada on how best to ensure that new technologies and products make their way to the Canadian marketplace. Minister Emerson also announced the appointment of Joseph Rotman, a member of CIHR's Governing Council and a business expert who specializes in the advancement of Canadian life sciences, as Chair of this panel.

May 19, 2005

• GeminX secures further financing in battle against cancer
  
  GeminX, a company co-founded in 1997 by Dr. Gordon Shore, from the Department of Biochemistry at McGill University, and Dr. Phil Branton, first Scientific Director of the CIHR Institute of Cancer Research, and dedicated to developing cancer treatments in the fight based on the regulation of cell death, has just secured over $65 million US in financing from private stakeholders. Today's GeminX announcement is a great example of CIHR's dedication to catalyzing commercial success for companies through its consistent funding support for health researchers.

May 18, 2005

• Researcher identifies hereditary colon cancer
  
  Dr. Jeremy Jass, a CIHR-funded researcher from McGill University, has identified a type of colon cancer that is hereditary. In 11 of hundreds of families tested, he discovered disease patterns on polyps that don't fit with the known inherited conditions: familiar adenomatous polyposis (FAP) and hereditary nonpolyposis colon cancer (HNPCC). This discovery will help in early-diagnosis and treatment of those patients at-risk. Montreal Gazette, March 3, 2005, p.A8.
  
  
• Study reveals that one in five seniors have kidney disease
  
  Newly disclosed data, unveiled by Dr. Bruce Culleton, a CIHR-funded Calgary-based nephrologist and kidney researcher, shows that one in five seniors suffer from kidney disease and that most of them don't even know it. The data was collected among older people aged 65 years and over from July to September, 2001. The Calgary Herald, March 4, 2005, p.A16.
  
  
• New treatment for neuropathic pain
  
  Dr. Ian Gilron, a CIHR-funded researcher from Queen's University, has discovered that a combination of two drugs, morphine and gabapentin, reduces pain suffered by specific neuropathic patients. Those patients who suffer diabetic neuropathy, a persistent burning pain in the soles of feet, or postherpetic neuropathy, pain that continues after herpes zoster and shingles infection leaves, experience 50 per cent less pain with both drugs than when the drugs are administered separately. The Kingston Whig-Standard, March 31, 2005, p.1.

May 13, 2005

• Clayman appointed Chair of PRE
  
  Dr. Alan Bernstein, CIHR President, along with Tom Brzustowski of Natural Sciences and Engineering Research Council of Canada (NSERC), and Marc Renaud, President of the Social Sciences and Humanities Research Council of Canada (SSHRC), are pleased to announce the appointment of Dr. Bruce P. Clayman as Chair of the Interagency Advisory Panel on Research Ethics (PRE). Dr. Clayman, who is President and CEO of Vancouver's Great Northern Way Campus, was chosen for his commitment to research ethics and was involved in the initial development of the Tri-Council Policy Statement for Research Involving Humans (TCPS).

• Stroke study recommends clot-busting drugs as treatment
  
  Based on extensive research findings, Dr. Michael Hill, co-author of the CIHR-funded Canadian Alteplase for Stroke Effectiveness Study (CASES) and a neurologist from the University of Calgary, recommends the use of tissue plasminogen activator (t-PA), a clot-busting drug, as a routine treatment for acute stroke. The findings will help hospitals develop better protocols for stroke treatments in Canada and around the world.
  
  
• The Interagency Advisory Panel on Research Ethics (PRE) -Call for Nominations for Members
  
  The Canadian Institutes of Health Research (CIHR), the Natural Sciences and Engineering Research Council of Canada (NSERC), and the Social Sciences and Humanities Research Council of Canada (SSHRC) are pleased to invite nominations of potential members to serve on the Interagency Advisory Panel on Research Ethics.  Deadline: June 6, 2005
  

• Narod listed as world's most cited researcher in field of breast cancer
  
  According to a survey conducted by ScienceWatch and the Institute of Scientific Information in Philadelphia, Dr. Steven Narod, a CIHR-funded, Canada Research Chair-holder at Toronto's Centre for Research in Women's Health, is the first Canadian researcher to top the list of the world's most cited scientists in the field of breast cancer. Best known for his research into the genetic susceptibility of breast cancer, Dr. Narod co-authored 193 scientific papers between 1994 and 2004, and has been cited 11,624 times by other researchers. The survey also lists that, in the field of breast cancer, five of the top six papers have Canadian authors, two of the top 20 institutions are Canadian and Canada ranks number one in terms of impact (citations per paper).
  

• International Joint Venture Project 2005 - Call for Project Outlines
  
  
• Researchers develop scale to measure autism
  
  Dr. Lonnie Zwaigenbaum, from the Offord Centre and McMaster Children's Hospital, along with Dr. Susan Bryson, at the IWK Health Centre/Dalhousie University, have developed the first, international CIHR-funded Autism Observation Scale for Infants (AOSI). The scale, which can map the development of six-month-old infants against 16 markers for autism, will help researchers find new treatments for these children.

May 5, 2005

• Janet Rossant named Chief of Research at Sick Kids
  
  Dr. Janet Rossant, CIHR Distinguished Investigator, Professor in the Departments of Medical Genetics and Microbiology and Obstetrics and Gynecology at the University of Toronto, as well as Senior Investigator at the Samuel Lunenfeld Research Institute, has been appointed Chief of Research at Toronto's Hospital for Sick Children (Sick Kids). As the Chair of CIHR's Working Group on Stem Cell Research, Dr. Rossant's research interests include embryonic stem cell development -which could have a positive impact on regenerative medicine and birth defects.
  
  
• Take a Deep Breath for World Asthma Day, May 3rd

April 27, 2005

• Howard Hughes Medical School's 2006 Grants for Biomedical Research
  
  
• Increased risk associated with combined artery surgeries
  
  Dr. Michael D. Hill, a CIHR-funded researcher from the University of Calgary, has determined that combining coronary artery bypass graft (CABG) surgery and carotid endarterectomy (CEA) can increase the risk of stroke.
  
  
• Naylor named President of U of T
  
  Dr. David Naylor, a Rhodes Scholar, Dean of Medicine for the University of Toronto and former member of CIHR's Governing Council, has been selected as the institution's new President. As an internationally recognized researcher, Dr. Naylor has served on several peer review, scientific advisory and policy committees. As chair of the National Advisory Committee on SARS and Public Health in 2003, he authored a report that led to the creation of the Public Health Agency of Canada.

April 22, 2005

• Canada-Finland-China Collaborative Program in Neuroscience
  
  
• CIHR-NIH Conference on the Biology of Manual Therapies
  
  
• Islet transplantation helps diabetes patient
  
  In Kyoto, Japan, Dr. James Shapiro, a CIHR-funded researcher from the University of Alberta, assisted Dr. Shinichi Matsumoto, from the Kyoto University Hospital Transplantation Unit, in successfully transplanting 400,000 islet cells, which produce insulin, from a living donor into a patient suffering from Type 1 diabetes. So far, the transplantation, which is an international first, has freed the patient from her dependency on insulin - and could represent the beginning of another therapeutic option.
  
  
• Study supports newly approved breast cancer therapy
  
  Dr. Kish Wasan, a CIHR-funded University/Industry Research Chair from the University of British Columbia, and his team, have confirmed that a recently approved breast cancer prevention treatment may not increase the risk of cardiovascular disease.

April 21, 2005

• Finding genetic roots to Restless Legs Syndrome
  
  Dr. Alex Desautels, a CIHR-funded researcher from the University of Montreal, has determined that a gene on chromosome 12q, and possibly one other gene, can cause restless legs syndrome (RLS). RLS is a syndrome that involves involuntary leg movements due to uncomfortable and unpleasant sensations - and this discovery offers a new starting point in the search for its genetic roots.

April 12, 2005

• Strong wins Sheila Essey award for ALS research
  
  Dr. Michael Strong, a CIHR-funded professor at the University of Western Ontario and scientist at the Robarts Research Institute, has been awarded the prestigious Sheila Essey award for research into amyotrophic lateral sclerosis (ALS), or "Lou Gehrig's Disease." Dr. Strong is only the second Canadian to take home the award that honours an individual who has made a significant contribution to treating, preventing or trying to find a cure for ALS. The London Free Press, April 11, 2005

April 11, 2005

• CIHR reorganizes the Funding Opportunities content on its web site
  
  
• Rat study shows that soy diet given to mothers may help the hearts of their offspring during adulthood

April 8, 2005

• World Health Day 2005: Healthy Mothers and Children

April 5, 2005

• CIHR is proud to support the Ottawa Regional Science Fair

April 4, 2005

• Involving the Canadian public in CIHR peer review committees
  
  
• The CIHR Knowledge Translation Award

March 15, 2005

• CIHR-NSERC Collaborative Health Research Projects (CHRP) announcement 

March 2, 2005

• NHLBI and CIHR co-sponsor international workshop on health of Arctic peoples
  
  The NIH National Heart, Lung, and Blood Institute (NHLBI) and the CIHR co-sponsored an international Working Group entitled "Research with Arctic Peoples: Unique Research Opportunities in Heart, Lung, Blood and Sleep Disorders" to address the following objectives: (i) research priorities for heart, lung, blood, and sleep disorders related to Arctic peoples; (ii) barriers and solutions to Arctic research; and, (iii) facilitating international comparisons.  Recommendations from the Working Group will be available to health agencies, within and among Arctic countries, in the coming year to advance the health research agenda for Arctic Peoples. 
  
  
• Gene mutations may cause schizophrenia recurrence
  
  Dr. Philip Seeman, a CIHR-funded researcher from the University of Toronto, has discovered that any genetic mutations can affect the brain's dopamine receptors and lead to psychosis (such as recurring hallucinations in schizophrenia). Given that dopamine is a neurotransmitter that allows people to move, think and feel, the next step for researchers is to discover the mechanism that causes the brain to become overly-sensitive in the first place.
  
  
• Electron photography possible through laser technology
  
  With the help of an international research team, Dr. J. C. Kieffer, a researcher from Institut national de la recherche scientifique who is currently funded through CIHR's Regenerative Medicine and Nanomedicine Initiative, has co-discovered a method of using tomographic imaging (x-rays) to photograph three dimensional structures of something as small as an electron. This discovery, thanks to pulsating laser beams, will give researchers insight into the bonds of molecules and their change during a chemical reaction.

February 28, 2005

• Update to September 2004 operating grants funding decisions
  
  
• CIHR announces the launch of the following Request for Applications (RFA): Toward Canadian Benchmarks for Health Services Wait Times - Evidence, Application and Research Priorities 
  

February 25, 2005

• CANADA HOPE Scholarship Program:  The deadline for full applications has been extended to March 15, 2005

February 24, 2005

• Message from the President of CIHR on Federal Budget 2005
  
  
• CIHR is renewing membership for its thirteen Institute Advisory Boards (IABs). A turnover of about 40 of the 215 members is expected. Information on application to become an IAB member is available at: How to apply to become an IAB member. Important: The application process for the 2005 cycle of IAB membership renewal occurs from February 24, 2005 until March 31, 2005.
  

February 23, 2005

• Budget 2005

February 21, 2005

• CIHR Strategic Training Program wins American Psychological Association award
  
  CIHR-funded researchers have won the American Psychological Association (APA) Award for Innovative Practices in Graduate Education. The researchers earned the award for the interdisciplinary CIHR Strategic Training Program entitled "Communication and Social Integration in Healthy Aging." Dr. Bruce Schneider, Professor of Psychology at the University of Toronto, is the principal investigator leading this program, which links researchers from six different Canadian universities. The APA committee (composed of representative from their Board of Educational Affairs and the Council of Graduate Departments of Psychology) was impressed with the interdisciplinary training the program gave students and its emphasis on knowledge translation issues.

February 18, 2005

• Study determines link between SSRI anti-depressants and risk of suicide
  
  
• New Committee: Palliative and End of Life Care

February 17, 2005

• Congratulations to the latest Order of Canada appointees!

February 16, 2005

• Major research discovery on bone loss

February 14, 2005

• CIHR expects to launch the following Request for Applications (RFA) in February 2005

February 9, 2005

• External review of CIHR
  
  
• Recent modification to the "Genomic Medicine and Human Development Operating Grants" RFA

February 8, 2005

• Bernstein appears on RCI's Sci-Tech Files
  
  On February 4, Dr. Alan Bernstein appeared on Sci-Tech Files, produced by Radio-Canada International. In this particular edition, Dr. Bernstein addressed how CIHR continues to improve international collaborations among researchers through initiatives such as the CANADA-HOPE scholarship program. The CANADA-HOPE program will enable promising scientists from low and middle income countries (LMC) to be exposed to some of the best Canadian science, laboratories and training environments - which should lead to the creation of sustainable treatment programs for people in developing countries.

February 1, 2005

• Measuring the effects of cancer fighting drugs
  
  An international team, led by CIHR-funded Dr. Bob Kerbel from Toronto's Sunnybrook and Women's College Health Sciences Centre, have discovered a way to measure the effects of a new class of drugs that help to prevent angiogenesis, or blood vessels that feed tissues (such as cancerous tumours). This could help improve the effectiveness of cancer fighting drug therapy. BNW, January 18, 2005
  
  
• Lack of drug intake increases drug-resistance with HIV patients
  
  Dr. Richard Harrigan, a CIHR-funded researcher from the BC Centre for Excellence in HIV/AIDS, has discovered that HIV patients who pick up and take their medications 90 per cent of the time are least likely to develop a drug resistance as those who take their drugs only 80 to 90 per cent of the time. The study emphasizes the importance of following drug regimens as closely as possible. The Vancouver Sun, January 13, 2005, p.B1
  
  
• Relieving pain through endocannabinoids
  
  Dr. Keith Sharkey, along with a CIHR-funded research group from the University of Calgary, is investigating what kind of role endocannabinoids, or tiny fatty acids in the brain that imitate all of the behaviours of marijuana, play in relieving nausea and vomiting. Their results could lead to treatments that will benefit cancer patients who suffer those kinds of side effects due to chemotherapy or radiation. The Ottawa Citizen, December 12, 2004, p.A4
  
  
• Trying to regulate diabetes in obese people
  
  Dr. Timothy Kieffer, from the University of British Columbia, is undertaking a three-year study that will examine leptin, a hormone produced by fat cells that regulates body weight and might play a role in blood sugar levels. His research could lead to effective treatments for obese people. The Vancouver Sun, January 11, 2005, p.A1.
  
  
• New funding for Target Obesity
  
  CIHR, along with the Heart and Stroke Foundation of Canada and the Canadian Diabetes Association, have awarded $1.4 million in financial support to the Target Obesity initiative, where 14 scientists intend to study the biological, social and behavioural factors influencing obesity. Research results here could lead to innovative ways to fight the obesity epidemic and its consequences, including diabetes and heart disease. The Globe and Mail, December 28, 2004

January 31, 2005

• The Strategic Training Initiative in Health Research (STIHR) webpage is now available

January 28, 2005

• CIHR webforms and Common CV - Problem with pop-up blockers
  
  
• CIHR's September 2004 operating grants competition yields highest-ever number of applicants
  
  
• The highlights of the funding, detailed lists of successful applicants and other decisions for the September 2004 competitions are now available
  
  
• Government of Canada has declared 2005 the Year of the Veteran

January 27, 2005

• CIHR Institutes and International partners collaborate to fund autism research
  
  CIHR Institutes of Neurosciences, Mental Health and Addiction (INMHA), Human Development, Child and Youth Health (IHDCYH), and Genetics (IG); in collaboration with the National Institute of Mental Health (NIMH) initiative lead for the National Institutes of Health (NIH), Health Research Board, Ireland (HRB), Southwest Autism Research & Resource Center (SARRC), Cure Autism Now (CAN), and the National Alliance for Autism Research (NAAR) have launched a joint Request for Application (RFA) to solicit applications to identify specific genes and gene variants in localized chromosomal regions that confer susceptibility to autism. 

January 26, 2005

• The Highlights of the funding and other decisions for the September 2004 competitions are now available.  The detailed lists of successful applicants will be available on Friday January 28th.
  
  
• International study-building bridges through research collaboration
  
  The successful work of the Canada International Scientific Exchange Program (CISEPO), a CIHR-funded international study is now published in the online version of the prestigious British journal, The Lancet.  
  
  COSEPO, which is based at Mount Sinai Hospital and the University of Toronto, has expanded its work from an inaugural joint Arab and Israeli professional association that researches hearing loss into an association that examines other health issues, including: the health of mothers, children and young people, nutrition and infectious diseases. 

January 25, 2005

• CIHR launches telephone survey of researchers in February 2005

January 21, 2005

• Dr. Tony Pawson awarded 2005 Wolf Prize in Medicine
  
  Due to his work in understanding how transmission of information among cells can break down and lead to malignancy, Dr. Anthony Pawson, a CIHR-funded Distinguished Investigator from Toronto's Samuel Lunenfeld Research Institute, has been named one of three recipients of the 2005 Wolf Prize in Medicine. The Wolf Prizes which were established in 1978 by the late Dr. Ricardo Wolf, a German-born inventor, who was also a diplomat and a philanthropist, rewards "outstanding scientists and artists for achievements in the interest of mankind and friendly relations among people."

January 20, 2005

• Extension of the Operating Grants registration deadline

January 18, 2005

• Minister Dosanjh Releases New Federal Initiative to Address HIV/AIDS

January 4, 2005

• General Announcement for ResearchNet/eSubmission pilots
  
  CIHR is adopting a new approach to providing electronic services to the research community. The centerpiece of CIHR's eServices' vision is a portal, ResearchNet, which will function as a virtual meeting place for the research community to obtain funding or information, and to actively share, collaborate, or complete administrative tasks.